Is a 97.7% drop in PSA after hormone therapy unusual? What does it mean?

My father was diagnosed with prostate cancer about 6 months ago. His psa was 898. The cancer had spread up to his collar bone, spine and his lymph nodes were swollen. After two lupron shots, his psa is now 2.5. Our family is so excited! The doctor’s office seemed pretty surprised at the major drop. Does that mean he may not have the cancer anymore? Also, is that big of a drop unusual? The doc’s staff said they’d not seen that big a drop but the doc was very nonchalant about it.

3 Responses to “Is a 97.7% drop in PSA after hormone therapy unusual? What does it mean?”

  • god knows and sees else Yahoo:

    GOOD!
    Lupron basically shuts down antigen production which is detected as part of the Prostate Specific Antigen (PSA).
    2.5 is great. Thats normal!
    But it only means that the Postate is shrinking, AND not growing and not out of control anymore.
    The Doc was nonchalant because its no big deal and its great!

  • joe b:

    i dont know?

  • Joe:

    Hi! wow that sounds like wonderful news! how’s he doing?! my dad underwent threatment for prostate cancer in 2006 and well last year his PSA’s went up again. :( he just had his first Lupron injection today and his PSA is only around 21. It’s stage 4, in his spine, some ribs, and other bones. i hope we’re as successful! :)

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